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. 2021 Feb 1;6:22. doi: 10.1038/s41541-021-00283-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a–c Fecal consistency was scored at indicated time points for each group. d, e PEDV shedding in feces was tested by RT-qPCR and reported as the relative viral loads determined by the standard curve. f The averaged body weight gain of piglets on indicated days post-challenge in each group was calculated by comparison with body weight of animals on the day of the challenge. g–j The neutralizing antibody titers, relative viral loads, and diarrhea scores were plotted together for individual piglets in different vaccination groups. The meaning of error bars and marked signs were described in the “Methods” section.