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. 2020 Jul 6;17(4):1813–1824. doi: 10.1007/s13311-020-00874-x

Fig. 4.

Fig. 4

Allopregnanolone increased neurogenesis in 3xTgAD mice. Allo treatment increased the number of immature neurons (BrdU+DCX+) in both hippocampal DG (A) and SVZ (B) of 3xTgAD mice. (C) Western blot assay confirmed that Allo treatment increased DCX protein expression by 30% (129.6% (97.27% < μ < 162%)) compared to Veh group (100% (90.9% < μ < 109.1%), p = 0.040, n = 5). The scatterplot represents mean values ± 95% CI