Fig. 2. Maternal TRZ exposure greatly elevates 7-DHC derived oxysterols in the brains of offspring.
P0 brain tissue of newborn pups was analyzed by LC–MS/MS to measure 7-DHC-derived oxysterols: A 4α-OH-DHC, B DHCEO, and cholesterol-derived oxysterol C 24-OH cholesterol. D, E Correlation of 7-DHC and 7-DHC derived oxysterols. F Correlation of cholesterol and cholesterol derived oxysterol. Each symbol corresponds to an individual pup brain; pink and blue symbols denote females and males, respectively. Statistical analysis: Table 3.