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. 2021 Feb 1;11:85. doi: 10.1038/s41398-021-01217-w

Table 2.

Three-way ANOVA of factors influencing brain sterol levels in newborn pups.

ANOVA table 7-DHC Desmosterol Cholesterol
Trazodone treatmenta P < 0.0001 P < 0.0001 P = 0.005
Maternal Dhcr7 genotypeb P = 0.8237 P = 0.132 P = 0.0822
Pup Dhcr7 genotypeb P < 0.0001 P < 0.0001 P = 0.1316
Trazodone * Maternal Dhcr7 genotype P = 0.8676 P = 0.09 P = 0.3774
Trazodone * Pup Dhcr7 genotype P < 0.0001 P = 0.0093 P = 0.2518
Maternal Dhcr7 genotype * Pup Dhcr7 genotype P = 0.8658 P = 0.1991 P = 0.7382
Trazodone * Maternal Dhcr7 genotype * Pup Dhcr7 genotype P = 0.8966 P = 0.9108 P = 0.7932

aTRZ versus DMSO alone.

bWT versus heterozygous for DHCR7.

Bold values indicates statistically significant.