Fig. 3.

Histopathological and immunohistochemical (IHC) findings and the result of in situ hybridization (ISH) for Epstein-Barr virus (EBV)-encoded small ribonucleic acid (EBER). The black bar indicates 100 μm.

Prominent lymphocytes and plasma cell infiltration are seen around the interstitium with hematoxylin and eosin staining.

b, c) Lymphocytes are positive for both CD3 (b) and CD20 (c) in the IHC study.

d) p40 is slightly positive.

e) Programmed death-ligand 1 (PD-L1) is moderately positive.

f) EBER-ISH is strongly positive.