TABLE 3.
Mouse anthropometrics and contractile properties of TA muscle
| Control | Control + exercise | Fucoidan | Fucoidan + exercise | |
|---|---|---|---|---|
| Body mass BM (g) | 29.51 ± 0.56 | 28.29 ± 0.46 | 29.31 ± 0.75 | 28.14 ± 0.59 |
| Body mass gain (%) | 6.71 ± 1.98 | 4.45 ± 3.37 | 1.52 ± 4.48 | 1.72 ± 2.46 |
| TA mass MM (mg) | 51.81 ± 1.37 | 53.94 ± 2.62 | 56.15 ± 1.45 | 55.10 ± 2.17 |
| MM:BW ratio | 1.76 ± 0.06 | 1.91 ± 0.10 | 1.92 ± 0.10 | 1.96 ± 0.08 |
| Pt (mN/mm2) | 57.3 ± 2.05 | 61.82 ± 3.94 | 56.8 ± 3.87 | 58.46 ± 4.16 |
| TPT (ms) | 253.36 ± 10.35 | 246.77 ± 5.64 | 245.8 ± 7.60 | 251.16 ± 8.44 |
| Dx/Dt (mN/ms) | 32.14 ± 1.11 | 30.11 ± 0.99 | 32.45 ± 1.04 | 29.59 ± 2.36 |
| ½ RT (ms) | 18.30 ± 1.40 | 19.67 ± 1.8 | 17.02 ± 0.96 | 18.57 ± 2.13 |
| Po (mN) | 1610 ± 47.15 | 1595 ± 52.79 | 1728 ± 38.91 | 1683.16 ± 29.49 |
| TA fatigue index | 0.82 ± 0.01 | 0.81 ± 0.03 | 0.84 ± 0.03 | 0.82 ± 0.05 |
| FS50 (Hz) | 34.84 ± 1.44 | 34.93 ± 0.76 | 38.12 ± 0.75 | 38.99 ± 1.56 |
| EDL CSA (µm2) | 2853.11 ± 743.21 | 3047.69 ± 643.68 | 3400.06 ± 868.85* | 3272.43 ± 758.09* |
| Soleus CSA (µm2) | 1810.95 ± 636.64 | 1730.20 ± 695.57 | 2034.19 ± 766.55* | 3272.48 ± 758.09* |
Values shown are mean ± SEM. n = 8 for control, n = 10 for fucoidan, n = 10 for control + exercise, and n = 10 for fucoidan + exercise.
Abbreviations: TA, tibialis anterior, CSA, cross‐sectional area, Pt, maximum twitch force, TPT, time to peak twitch, Dx/Dt, rate of twitch force development, ½ RT, one‐half relaxation time, Po, maximum tetanic force, FS50, stimulation frequency to achieve 50% of maximal force.
*
p < .05 compared to control.