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. 2020 Dec 25;20:34–47. doi: 10.1016/j.omto.2020.12.012

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Expression of immune checkpoint molecules (ICMs) and predictions of immunotherapy responsiveness of PGs

(A and D) Expression levels of six ICMs among ISs in both the CBTTC (A) and ICGC (D) cohorts. (B and E) Comparisons of the proportion of responders to immunotherapy among different subgroups, including the ISs and WHO grades in both the training (B) and validation (E) sets. (C and F) Subclass mapping analysis for predicting the likelihood of a response to ICB therapy for the ISs in the CBTTC (C) and ICGC (F) cohorts. R, response to ICB (Bonferroni corrected p value < 0.05); noR, no response to ICB (Bonferroni corrected p value > 0.05).