Table 2.

Univariate and multivariate logistic regression analyses for identifying risk factors and IS predictors for pediatric gliomas

Variables	Univariate analysis				Multivariate analysis
	Β	OR (95% CI)	p value		β	OR (95% CI)	p value
IS-I
Intercept					1.34	3.81 (1.91−8.37)	3.73e−04a
AC060834.2	0.73	2.09 (1.01−12.10)	0.24
AC113418.1	−1.46	0.29 (0.10−2.37)	0.28
AL353747.4	−2.99	0.14 (0.08−5.39)	0.17
CCL18	1.84	1.53 (1.32−1.73)	0.041a		4.87	1.34 (1.13−1.55)	1.57e−03a
FOXR2	−1.46	0.46 (0.11−3.78)	0.10
GTF3AP6	−3.26	0.79 (0.24−1.35)	0.39
IGHEP1	6.86	9.55 (1.48−1,842)	0.88
IGKV2-29	2.84	17.10 (1.46−605)	0.16
IGKV3-15	0.87	1.09 (0.19−15.6)	0.95
IGLV2-11	0.29	1.34 (0.54−3.69)	0.55
IGKV3D-20	0.38	1.46 (0.68−5.96)	0.46
SIGLEC6	1.49	3.16 (2.38−3.93)	3.48e−06a		11.19	7.31 (4.90−9.52)	1.05e−09a
IS-II
Intercept					−1.59	0.20 (0.10−0.37)	1.49e−06a
POU4F1	−0.65	0.53 (0.03−1.01)	0.15
IGFN1	−0.93	0.41 (0.32−0.49)	0.033a		−1.27	0.28 (0.09−0.58)	5.30e−03a
IGHV3-7	−0.70	0.79 (0.43−1.16)	0.38
IGKV3-15	−0.20	0.98 (0.67−2.19)	0.98
SIGLEC6	−7.01	0.57 (0.41−0.76)	2.49e−04a		−7.23	0.72 (0.62−0.88)	8.37e−06a
WDR72	−6.37	0.90 (0.55−1.27)	0.12
AL020995.1	2.76	1.58 (0.63−7.59)	0.11
GTF3AP6	−2.61	0.84 (0.65−1.10)	0.86
IS-III
Intercept					−1.17	0.38 (0.11−0.62)	1.64e−10a
POU4F1	1.06	2.88 (0.33−3.07)		0.37
AL354863.1	1.37	3.02 (0.12−34.81)		0.72
GLOD5	−4.34	0.12 (0.01−3.96)		0.35
DNAJC5G	−0.43	0.64 (0.09−20.07)		0.69
CD3D	−5.34	0.48 (0.06−14.08)		0.23
GZMH	−5.04	0.65 (0.53−0.77)		0.012a	−3.07	0.46 (0.11−0.68)	0.036a
CD2	−5.93	0.26 (0.21−0.42)		0.023a	−6.08	0.23 (0.15−0.31)	0.021a
HLA-DQA1	−4.31	0.44 (0.30−0.79)		0.027a	−4.26	0.14 (0.08−0.21)	4.42e−03a
KRT34	7.23	1.38 (0.33−2.61)		0.64
NEUROD6	3.95	5.19 (0.02−43.34)		0.50
GTF3AP6	1.04	1.95 (0.77−3.45)		0.99
FCER1A	−4.82	0.81 (0.73−0.91)		0.003a	−3.88	0.21 (0.09−0.36)	0.010a
C7	−0.20	0.82 (0.36−1.13)		0.73
CLEC12A	−0.25	0.77 (0.01−16.93)		0.89
MAGEA11	2.13	1.40 (0.60−7.45)		0.86

β, regression coefficient; OR, odds ratio; 95% CI, 95% confidence interval.

^ap < 0.05.