Table 3.
The Radiobiological Parameters of the NSCLC Cells Treated With or Without ECL Before Irradiation
| A549 | COR-L23 | |||||
|---|---|---|---|---|---|---|
| X-Ray | X-Ray + ECL (IC20) | X-Ray + ECL (IC50) | X-Ray | X-Ray + ECL (IC20) | X-Ray + ECL (IC50) | |
| SF2 | 0.51 ± 0.06 | 0.28 ± 0.05 | 0.19 ± 0.03 | 0.56 ± 0.01 | 0.36 ± 0.03 | 0.23 ± 0.04 |
| D10 | 4.45 ± 0.67 | 3.60 ± 0.52 | 3.31 ± 0.20 | 4.90 ± 0.14 | 3.81 ± 0.09 | 3.22 ± 0.13 |
| SER10 | 1.00 ± 0.00 | 1.24 ± 0.02 | 1.34 ± 0.14 | 1.00 ± 0.00 | 1.29 ± 0.01 | 1.52 ± 0.10 |
SF2, survival fraction at 2Gy; D10, the dose required to obtain a survival level of 10%; SER10, sensitizer enhancement ratio at 10% surviving fraction. Values were calculated with linear-quadratic model and presented as mean ± SD of three independent experiments.