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. 2020 Sep 1;28(4):409–421. doi: 10.3727/096504020X15868639303417

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Copyright © 2020 Cognizant, LLC.

This article is licensed under a Creative Commons Attribution-NonCommercial NoDerivatives 4.0 International License.

PMC Copyright notice

TRIM46 expression is upregulated in osteosarcoma (OS) tissues and associated with survival time. (A) TRIM46 expression in OS and their normal bone counterpart tissues based on the E-MEXP-3628 dataset. (B) TRIM46 expression in OS tissues and bone cysts (BC) from our independent hospital cohort 1 was analyzed by quantitative polymerase chain reaction (qPCR). (C) Representative TRIM46 expression in OS tissues (T1, T2, T3, and T4) and bone cysts (BC1, BC2, BC3, and BC4) from our independent hospital cohort 1, as analyzed by Western blotting. (D) Immunohistochemistry (IHC) staining for TRIM46 in OS tissues from our independent hospital cohort 2. Scale bar: 50 μm. (E) Survival analysis of patients from our independent hospital cohort 2. *p < 0.05, ***p < 0.001 compared with normal or BC.