FIG 1.

Feeding SP reduces the development and severity of SK and angiogenesis after HSV-1 infection. SK and angiogenesis were recorded for each eye of C57BL/6 mice orally fed SP (n, 9 mice) or not (control group; n, 10 mice) after infection with HSV-1. (A, B) The severity of SK (A) and angiogenesis (B) were recorded at days 0, 7, 11, and 15 p.i. (C, D) The severity of SK (C) and angiogenesis (D) was recorded for individual eyes at the 15th day p.i. Data represent mean results ± SEM. All data were analyzed by an unpaired Student t test, and significance levels were determined (*, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001).