FIG 5.
Neutralization ability of COBRA SVP vaccines in preimmune NHPs. Shown are FRNT50 values for individual DENV-preimmune NHPs given COBRA 1 SVP (a), COBRA 2 SVP (b), and COBRA tetravalent SVP (c) vaccinations. Each graph represents a different genotype. DENV serotypes are indicated on the x axis. Dashed lines indicate a 1:100 titer. Unfilled bars, day 0; filled bars, day 70.