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Predicted binding modes of ligands in lcT2R01 and drT2R3a. Predicted binding modes of taurolithocholic acid (colored in cyan) into lcT2R02 (A) and of denatonium (colored in green) and saccharine (colored in orange) into drT2R3a (B). 3D representations show how the ligand is accommodated in the binding site, ligand–receptor interactions (including π–π stacking interactions, salt bridges and hydrogen bonds) are detailed in the 2D diagrams.
