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. 2021 Jan 19;11:612478. doi: 10.3389/fphar.2020.612478

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Copyright © 2021 Dong, Qin, Ma, Cui, Chen, Hou, Chen, God’spower, Eliphaz, Qin, Guo, Ding and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of antidiarrhea mechanism of the effective components of Plantago asiatica L. (A,B) Castor oil-induced intestinal fluid accumulation. (C,D) Changes in Na⁺/K⁺-ATPase and creatine kinase activities in the small intestine of rats. (E) The quantitative PCR. Relative gene expression>1 represents upregulating gene. In contrast, relative gene expression <1 represents a downregulating gene. (F–G) Changes in sodium and potassium ion concentrations in the small intestine of rats. (H) Charcoal meal model of intestinal motility. Data are presented as the means ± SD from five groups. Different small letter superscripts in the same column indicate significant differences at p < 0.05. NS indicates no significant differences.