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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Breast Cancer Res Treat. 2020 Apr 10;181(2):297–307. doi: 10.1007/s10549-020-05629-y

Fig. 3.

Fig. 3.

Metastasis progression and host animal survival after intracardiac injection of NOD-SCID-gamma (NSG) female mice with MCF-7 breast cancer cells expressing luciferase and mutant D538G ER. After injection of 0.5 x 106 cells, animals were treated 6-times per week with vehicle or K-07 (80 mg/kg orally for 30 days and then 40 mg/kg). (a) Metastatic load was monitored at 25 days by bioluminescence (IVIS) imaging after luciferin injection, and (b) animal survival was followed to 70 days.