Table 3.
Associations between mean serum antioxidant concentrations and F2-isoprostane (per 1 unit increase) and symptom scores by cycle
| Symptoms score | Vitamin A (ug/dL) | Vitamin C (ug/dL) | α-tocopherol (ug/dL) | γ-tocopherol (ug/dL) | F2-isoprostane (pg/mL) |
|---|---|---|---|---|---|
| β (95% CI), per ug/dL | β (95% CI), per ug/dL | β (95% CI), per ug/dL | β (95% CI), per ug/dL | β (95% CI), Per 10 pg/dL | |
| Depression | − 1.92 (− 4.19, 0.34) | − 0.03 (− 0.39, 0.33) | − 0.05 (− 0.13, 0.03) | − 0.15 (− 0.46, 0.16) | 0.07 (0.02, 0.12)a |
| Anxiety | − 0.72 (− 2.97, 1.53) | 0.08 (− 0.25, 0.41) | 0.01 (− 0.07, 0.09) | − 0.14 (− 0.42, 0.15) | 0.05 (0.003, 0.10) |
| Fluid retention/hydration | − 1.02 (− 2.12, 0.08) | 0.02 (− 0.15, 0.20) | − 0.01 (− 0.04, 0.02) | − 0.11 (− 0.25, 0.04) | 0.01 (− 0.01, 0.03) |
| Craving | − 2.33 (− 6.69, 2.03) | − 0.08 (− 0.72, 0.57) | 0.004 (− 0.15, 0.16) | − 0.33 (− 0.88, 0.23) | 0.16 (0.10, 0.22)a |
| Pain | − 3.18 (− 7.03, 0.68) | − 0.06 (− 0.77, 0.65) | − 0.05 (− 0.19, 0.08) | − 0.45 (− 0.94, 0.04) | 0.05 (− 0.06, 0.16) |
| Other | − 1.55 (− 3.59, 0.49) | 0.31 (0.001, 0.63)a | − 0.01 (− 0.08, 0.06) | − 0.24 (− 0.50, 0.01) | 0.03 (− 0.01, 0.07) |
Adjusted for energy intake, age, BMI, race, physical activity, smoking, alcohol intake, and pain reliever use. Bold indicates statistically significant after adjusting for multiple comparisons using the False Discovery Rate
aIndicates statistical significance at the 0.05 level