Table 1.
Baseline characteristics
| Characteristic | All Patients (n = 94) |
|---|---|
| Age, years | 48 ± 19 |
| Sex, male, n (%) | 58 (61.7) |
| Race, n (%) | |
| • White | 83 (88.3) |
| • Black | 3 (3.2) |
| • Asian | 8 (8.5) |
| Location, n (%) | |
| • Outpatient | 43 (45.7) |
| • Inpatient medical ward | 49 (52.1) |
| • ICU | 2 (2.1) |
| Charlson co-morbidity index | 1.9 ± 2.1 |
| Baseline B. melitensis antibody titera | > 1:1280 [1:1280- > 1:1280] |
| Baseline B. melitensis antibody titer ≥1:640, n (%) | 78 (83) |
| Baseline B. abortus antibody titera | > 1:1280 [1:1280- > 1:1280] |
| Baseline B. abortus antibody titer ≥1:640, n (%) | 73 (77.7) |
| Baseline temperature, °C | 36.8 [36–37.3] |
| Baseline white blood cells count, cells/mm3 | 6.6 ± 4.9 |
| Baseline C-reactive protein, mg/L | 34.5 ± 39.9 |
| Baseline erythrocyte sedimentation rate, mm/hr | 29 ± 23.5 |
| Duration of therapya | 45 [45–135] |
| Risk factors for infection, n (%) | |
| • Unpasteurized dairy product | 42 (44.7) |
| • Direct contact with animals | 4 (4.3) |
| • Both | 8 (8.5) |
| • Other | 1 (1) |
| • Unknown | 39 (41.5) |
| Diagnostic test positivity, n (%) | |
| • Brucella serology alone | 42 (44.7) |
| • Both Brucella serology and culture | 52 (55.3) |
| Brucella spp., n (%) | |
| • B. melitensis | 4 (4.3) |
| • B. abortus | 2 (2.1) |
| • Both | 88 (93.6) |
| Complicated brucellosis, n (%) | 29 (30.9) |
| • Spondylodiscitis | 17 (59) |
| • Neurobrucellosis | 5 (17) |
| • Orchitis | 3 (10.3) |
| • Other | 3 (10.3) |
| • > 1 organ | 1 (3.4) |
| Arthralgia, n (%) | 30 (31.9) |
| Regimen used, n (%) | |
| • Aminoglycoside + doxycycline + rifampin | 44 (46.8) |
| • Doxycycline + rifampin | 34 (36.2) |
| • Other | 16 (17) |
Data are presented as mean ± SD unless specified otherwise
a Median [IQR]