Fig. 6.

MiR-144 suppresses HCC development in vitro and in vivo. a Functions of overexpression of miR-144 on Hep3B and Huh7 cells were determined by colony formation assay. b RTCA analysis of cells proliferation in two HCC cells (The vertical line represented the time of cell transfection). c Cells migration ability was assessed by wound healing assay. d Cells invasion ability was measured by transwell invasion assay. e Statistical analysis of the invaded cells. f Fluorescent photos of nude mice bearing HCC tumors. g Representative of HCC tumors from NC and miR-144 overexpression groups. h The tumor growth curves. i HCC tumor weight was measured. j Representative images of EIF4G2 IHC staining of mice tumor sections from NC and miR-144 group. * p < 0.05, **p < 0.01