Fig. 4.

Mutational landscape of EPHA7 in TCGA cohort. a Association of EPHA7 status and clinical characteristics in TCGA cohort. The cancer type, sex, age, CNA, TMB, PFS, and OS were annotated. Samples were sorted by EPHA7 status, while EPHA7-MUT and EPHA7-WT samples were separated by a gap. b The proportion of EPHA7-MUT tumors identified in each cancer type with at least one mutation case. Numbers above the barplot indicated the alteration frequency, and numbers close to cancer names indicated the number of EPHA7-MUT patients and the total number of patients. “Truncating mutations” included nonsense, splice site mutations, and frameshift insertion and deletion; “Non-truncating mutations” included missense mutations and inframe insertion and deletion