Table 5.

Physiological quotients between [saliva]/[plasma] and [plasma]/[CSF] of significant cytokines for group discrimination

Cytokine/chemokine	[Saliva]/[plasma]			[Plasma]/[CSF]
	Patient	Healthy control	Relative to controls	Patient	Healthy control	Relative to controls
MIP-1α	0.63 (0.15–1.38)	0.35 (0.02–0.98)	↑*	1.30 (0.78–1.86)	1.21 (0.79–1.89)	↑
IL-6	3.00 (0.15–21.23)	2.21 (0.11–10.40)	↑	1.47 (0.42–2.85)	0.74 (0.09–2.71)	↑*
IL-1β	502.12 (116.60-1764.62)	505.65 (53.26–1665.00)	↓	2.45 (0.48–5.50)	1.63 (0.24–10.82)	↑*
IL-1RA	0.38 (0.20–0.84)	0.40 (0.24–0.71)	↓	10.73 (6.03–24.88)	7.14 (4.20-12.43)	↑
TSLP	0.32 (0.18–0.47)	0.30 (0.12–0.61)	↑	1.55 (0.46–2.70)	1.78 (0.53–3.25)	↓
MIP-3β	0.01 (0.04–0.08)	0.06 (0.03–0.15)	↓	0.85 (0.17–1.90)	0.61 (0.23–1.02)	↑
MIP-1β	0.15 (0.03–0.38)	0.09 (0.02–0.22)	↑	3.70 (1.89–5.90)	3.90 (2.50–6.43)	↓
GRO-alpha	8.37 (1.45–44.80)	3.39 (0.18–22.15)	↑*	2.74 (0.98–8.96)	8.37 (0.79–28.08)	↓*
YKL-40	0.44 (0.11–0.70)	0.38 (0.04–0.74)	↑	0.85 (0.58–1.01)	0.74 (0.55–0.93)	↑*
M-CSF	3.88 (0.94–9.78)	2.56 (1.15–4.21)	↑	1.05 (0.80–1.38)	1.11 (0.62–1.75)	↓
MCP-3	1.22 (0.48–2.63)	1.97 (0.70–4.07)	↓	0.93 (0.59–1.23)	0.83 (0.68–1.07)	↑
IL-18	2.61 (0.20–8.46)	1.15 (0.21–3.09)	↑	122.99 (38.05-306.47)	104.26 (40.78-155.14)	↑
CTACK	0.00 (0.0008–0.005)	0.00 (0.00-0.01)	↑	122.22 (74.08-201.14)	106.56 (51.85–155.60)	↑
IL-13	0.46 (0.13–0.92)	0.59 (0.04–1.18)	↓	5.12 (1.34–11.21)	3.57 (1.25–13.99)	↑
ENA-78	0.06 (1.61–12.87)	3.01 (0.01–29.21)	↓	38.11 (2.20-141.85)	87.81 (2.98–327.60)	↓

Quotients for 15 out of 17 inflammatory substances presented in Table 3 are shown as 2 proteins, GRO-alpha and YKL-40, were presented twice in different biofluids. Data is presented as mean (range) where significant differences between groups (p < 0.05) are denoted with *, see "Regression of class discriminating inflammatory substances" section for exact figure