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[Preprint]. 2021 Feb 12:2021.01.25.428137. [Version 3] doi: 10.1101/2021.01.25.428137

Fig. 3 |. B.1.351 is more resistant to neutralization by convalescent plasma from patients.

Fig. 3 |

Fig. 3 |

a, Neutralization results for 20 convalescent plasma samples (P1–P20) against B.1.1.7, B.1.351, and WT viruses. Data represent mean ± SEM of technical triplicates. b, Fold increase or decrease in neutralization IC50 of B.1.1.7 and B.1.351, as well as UKΔ8, SAΔ9, and single-mutation pseudoviruses, relative to the WT presented as a heatmap with darker colors implying greater change. c, Change in reciprocal plasma neutralization IC50 values of convalescent plasma against B.1.1.7 and B.1.351, as well as UKΔ8 and SAΔ9, relative to the WT. Mean fold changes in IC50 values relative to the WT are written above the p values. Statistical analysis was performed using a Wilcoxon matched-pairs signed rank test. Two-tailed p-values are reported.