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. 2021 Jan 29:1–17. doi: 10.1080/07391102.2021.1876774

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Figure 14. — In silico immune simulation with the trivalent subunit vaccine. (A) Immunoglobulin production in response to antigen, (B) B-cell populations after exposure to antigen (C), The evolution of T-helper, (D) T-cytotoxic, and (E) T-regulatory cell populations per state after antigen injection. (F) Level of cytokines induced by the vaccine. The insert plot shows the IL-2 level with the Simpson index, D indicated by the dotted line.