Fig. 2.

Characterization of the biochemical and physical properties of the BM- and AD-ECMs using proteomic analysis and atomic force microscopy. (A) Relative abundance of types I, IV, V, VI, and XII collagen in BM- and AD-ECM based on mass spectrometric analyses. (B) Representative atomic force micrographs showing differences in topography, adhesion, and stiffness of the BM- and AD-ECMs. Each image represents a 40 × 40 μm region of the matrix. (C) Adhesion and stiffness (elastic modulus) of BM- and AD-ECM as measured by atomic force microscopy. Each data point represents one randomly selected independent measurement. The error bars represent the 95% confidence interval; the box and diamond represent the median of the samples.