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. 2020 Nov 2;13(3):123–128. doi: 10.4103/ojo.OJO_250_2019

Table 2.

Predictive factors of eye salvage by external beam radiation therapy after failure of chemotherapy and focal therapy

n Success rate Percentage 95% CI P
Salvaged 13 - 46 0.2953-0.6419 -
Enucleated 15 - - 0.3581-0.7047 -
Male 14 8 57 0.3255-0.7866 1.00
Female 10 5 50 0.2366-0.7634
Bilateral 20 patients, 24 eyes 12 50 0.3143-0.6857
Unilateral 4 1 25 0.0341-0.7109
Right eye 13 8 61 0.3541-0.8240 0.1228
Left eye 15 5 33 0.1496-0.5850
No vitreous seeds 10 9 90 0.5740->0.9999 0.0011
Vitreous seeds 18 4 22 0.0847-0.4575
IIRC (B, C) 10 7 70 0.3923-0.8967 0.1141
IIRC D 18 6 33 0.1610-0.5643
RE (I-IV) 6 4 67 0.2957-0.9075 0.6703
RE V 22 9 4 0.2321-0.6131
RE Va 6 5 83 0.4178-0.9886 0.0464
RE Vb 16 4 25 0.0971-0.4997
No Stage migration 9 (B, C) 6 6 100 0.5572-1.0000 0.0333
Stage migration (B, C) 4 1 25 0.0341-0.7109
8 cycles of CVE 14 7 50 0.2680-0.7320 1.00
6 cycles CVE 14 6 43 0.2134-0.6745

EBRT: External beam radiation therapy, IIRC: International Intraocular Retinoblastoma Classification,[16] RE: Reese-Ellsworth classification,[17] CVE: Carboplatin, vincristine, and etoposide chemotherapy, CI: Confidence interval