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. 2021 Jan 29;153(3):e202012604. doi: 10.1085/jgp.202012604

Figure S14.

Figure S14.

Active tension corrected for the decrease in titin force due to shortening of a half-sarcomere. The observed tension is usually corrected for resting tension associated with the force in titin and other parallel connective tissue. The observed tension (black line) after the subtraction of the resting tension is usually reported as active tension. However, the resting tension in titin and other passive components decreases the tension due to shortening of the half-sarcomere denoted as displacements. The decrease in the (titin) force (green line) during twitch effectively increases active force (red to pink line) by the same amount. Force per myosin filament from MUSICO simulations is shown in parallel with the observed tension.