Table 9.
Multivariable linear regression model for flavoprotein fluorescence heterogeneity in patients with diabetes.
| Factor | Estimate | 95% CI | p value | |
|---|---|---|---|---|
| Intercept | −0.24 | −0.79 | 0.32 | 0.409 |
| Age (years) | 0.02 | 0.01 | 0.02 | <0.001 |
| Gender: Female (vs Male) | 0.11 | −0.03 | 0.24 | 0.133 |
| Race | ||||
| Black (vs White) | −0.05 | −0.18 | 0.08 | 0.454 |
| Other (vs White) | −0.04 | −0.34 | 0.25 | 0.767 |
| Smoking Status | ||||
| Current (vs Never) | −0.26 | −0.51 | 0.00 | 0.051 |
| Former (vs Never) | −0.13 | −0.27 | 0.01 | 0.066 |
| Hemoglobin A1c (%) | −0.01 | −0.05 | 0.03 | 0.705 |
| Insulin use | 0.16 | 0.02 | 0.30 | 0.031 |
| Diabetic retinopathy stage | ||||
| Mild–moderate nonproliferative | 0.15 | −0.01 | 0.31 | 0.059 |
| Proliferative | 0.20 | 0.03 | 0.38 | 0.023 |
| Clinically significant diabetic macular edema | 0.15 | −0.11 | 0.42 | 0.264 |
Estimates denote the predicted change in flavoprotein fluorescence intensity for a 1 unit increase of a numeric factor, or for that factor level relative to reference level of a categorical factor, with other factors held constant.
Statistically significant values are bolded and italicized.
CI confidence interval.