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. 2020 Oct 8;46(2):413–422. doi: 10.1038/s41386-020-00876-5

Fig. 3. ABM300 (10 mg/kg) has no effect in the cannabinoid-induced tetrad, when compared to THC (10 mg/kg).

Fig. 3

Cannabinoid-induced tetrad measuring a percent inhibition of locomotor activity (15 min), b rectal temperature (°C), c catalepsy-induced immobility time (s), and d tail withdrawal (% MPE). ABM300 (10 mg/kg) alone has no effect on all outputs, when compared to vehicle and THC. All tests performed in male mice, ABM300 or THC were administered 30 min prior to behavioral testing via i.p. injection. Data shown as mean ± SEM, *p ≤ 0.05 compared to vehicle, ****p < 0.0001, one-way ANOVA, multiple comparisons, post-hoc Sidak’s test. Effect of treatment a F[2,27] = 37.47, p < 0.0001, b F[2,27] = 85.58, p < 0.0001, c F[2,27] = 13.72, p < 0.0001, and d F[2,26] = 46.67, p < 0.0001.