Table 1.
Clinical characteristics of healthy individuals and POAG patients.
| Healthy Individuals | POAG Patients | p-value | |
|---|---|---|---|
| Number | 79 | 164 | |
| Age (mean, SD) | 48.30 (15.18) | 49.00 (14.01) | 0.755 |
| Gender (male, %) | 27 (34.18) | 69 (42.07) | 0.238 |
| C/D ratio | 0.52 (0.12) | 0.77 (0.45) | <0.001 |
| VA | 1.10 (0.24) | 0.76 (0.30) | <0.001 |
| CCT (um) | 540.59 (25.81) | 540.42 (34.44) | 0.966 |
| AL (mm) | 24.67 (1.70) | 25.32 (2.17) | 0.012 |
| Mean IOP (mmHg) | 13.43 (2.57) | 17.36 (4.43) | <0.001 |
| Peak IOP (mmHg) | 15.96 (2.69) | 21.61 (5.45) | <0.001 |
| Trough IOP (mmHg) | 11.03 (2.53) | 13.95 (3.82) | <0.001 |
| SD of IOP (mmHg) | 1.49 (0.47) | 2.37 (0.97) | <0.001 |
| Max difference (mmHg) | 4.93 (1.63) | 7.60 (3.00) | <0.001 |
| AUC_IOP | 294.40 (56.88) | 379.40 (96.42) | <0.001 |
| MAPE (mmHg) | 2.45 (0.89) | 4.16 (1.90) | <0.001 |
Data are expressed as mean (SD) unless otherwise specified.
POAG primary open angle glaucoma, C/D ratio cup-to-disk ratio, VA visual acuity, CCT central corneal thickness, AL axial length, MAPE mean amplitude of IOP excursions, SD standard deviation, AUC_IOP area under curve of circadian IOP.