Table 1.

Definition of the SFS.

SFS element	Definition of element
RARR	One alternative copy, individual A heterozygous
RRRA	One alternative copy, individual B heterozygous
RARA	Two alternative copies, both individuals A and B heterozygous
AARR	Two alternative copies, individual A homozygous alternative
RRAA	Two alternative copies, individual B homozygous alternative
AARA	Three alternative copies, individual B heterozygous
RAAA	Three alternative copies, individual A heterozygous

“R” and “A” under the SFS element refer to reference and alternative alleles, respectively.