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. 2020 Jun 17;27(12):3289–3306. doi: 10.1038/s41418-020-0578-0

Fig. 2. vIRF1 increases CDCP1 expression.

Fig. 2

a Western blotting analysis of CDCP1 expression in HUVECs transduced with 2 MOI lentiviral vIRF1 (vIRF1) or control lentivirus (pHAGE). b Western blotting analysis of CDCP1 expression in HUVECs treated with PBS (PBS) or infected with KSHV wild-type virus (KSHV_WT) or K9 mutant virus (K9_Mut). c H&E staining and immunohistochemical staining of KSHV LANA, CDCP1 in normal skin, skin KS of patient #1 (Skin KS1), skin KS of patient #2 (Skin KS2), and skin KS of patient #3 (Skin KS3). Magnification, ×200, ×400. d Results were quantified in c. e Detection of vIRF1 and CDCP1 in skin KS of patient #1 (Skin KS1), skin KS of patient #2 (Skin KS2), and skin KS of patient #3 (Skin KS3) by immunofluorescence analysis (IFA). Data were shown as mean ± SD. ***P < 0.001, Student’s t-test.