Table 1.

List of the 35 genes with the highest Fst values fixed in the American populations.

Top	Gene	No. strains with the gene	No. strains (%)	Description	Fst max value	P99	No. positions >P99
1	HP0543	509	70.40	cag pathogenicity island protein cag22 (cagF)	0.5360	0.4507	3
2	HP0175	723	100.00	Putative peptidyl-prolyl cis,trans-isomerase (PpiC)	0.5018	0.2134	3
3	HP0181	723	100.00	CvpA family protein	0.4957	0.4683	3
4	HP0887	713	98.62	Vacuolating cytotoxin autotransporter (vacA)	0.4885	0.4226	13
5	HP0537	511	70.68	cag pathogenicity island protein cag16 (cagM)	0.4509	0.3841	4
6	id7111332	671	92.81	Hypothetical protein	0.4407	0.4399	1
7	HP0538	510	70.54	cag pathogenicity island protein cag17 (cagN)	0.4394	0.3144	4
8	id7531345	486	67.22	Hypothetical protein	0.4360	0.4304	1
9	HP0524	515	71.23	Type IV secretion system protein	0.4311	0.3095	7
10	HP0547	507	70.12	cag pathogenicity island protein cag26 (cagA)	0.4151	0.2604	9
11	HP0539	510	70.54	cag pathogenicity island protein cag18 (cagL)	0.4126	0.2929	3
12	HP0525	514	71.09	Type IV secretion system ATPase	0.4108	0.3719	3
13	HP0544	510	70.54	Type IV secretion/conjugal transfer ATPase	0.4092	0.2609	8
14	HP0130	722	99.86	Hypothetical protein	0.4039	0.2714	4
15	HP0486	723	100.00	Membrane protein	0.4014	0.3615	5
16	id10887	723	100.00	Putative protein	0.3974	0.2771	2
17	HP0528	509	70.40	cag pathogenicity island protein cag8 (cagX)	0.3901	0.3389	4
18	id970544	721	99.72	Hypothetical protein	0.3892	0.3860	1
19	HP1524	723	100.00	Lipoprotein	0.3852	0.1972	2
20	HP0686	709	98.06	Iron(III) dicitrate transport protein (FecA)	0.3816	0.2385	7
21	id71034	624	86.31	Lysine-specific permease	0.3758	0.2994	5
22	HP0706	723	100.00	Membrane protein	0.3705	0.3092	3
23	HP0559	723	100.00	Acyl carrier protein	0.3693	0.3655	1
24	HP0561	723	100.00	3-oxoacyl-ACP reductase	0.3684	0.2786	3
25	HP0523	517	71.51	cag pathogenicity island protein cag4 (cagg)	0.3622	0.2806	2
26	HP0722	691	95.57	Membrane protein	0.3549	0.3023	5
27	HP1012	722	99.86	Zn-dependent protease	0.3517	0.1692	5
28	HP0211	706	97.65	Beta-lactamase HcpA	0.3512	0.1825	4
29	HP0541	510	70.54	cag pathogenicity island protein cag20 (cagH)	0.3501	0.1942	4
30	HP0554	723	100.00	Hypothetical protein	0.3499	0.2827	4
31	HP0530	510	70.54	Type IV secretion system protein (cagV)	0.3484	0.3401	3
32	HP0534	510	70.54	cag pathogenicity island protein cag13 (cagS)	0.3460	0.2943	2
33	HP1055	721	99.72	Membrane protein	0.3438	0.2876	4
34	HP1243	520	71.92	babA	0.3434	0.2758	4
35	HP0522	520	71.92	cag pathogenicity island protein cag3 (cagd)	0.3416	0.2749	6