Fig. 2. Sepn1 KO mice show defective exercise endurance and increased muscle glucose metabolism during exercise.
a Maximal treadmill running distance for 2-month-old mice of indicated genotype (N = 12). b Plasma glucose in mice of indicated genotype at rest and 20 min after exhaustive running was tested (N = 12). c Representative periodic acid-Schiff (PAS) staining in liver and gastrocnemius muscle sections from mice of indicated genotype, at rest and after running. Insets represent samples digested with amylase.