Table.
Demographic characteristics, comorbidities and laboratory parameters in survivors and non-survivors at the time of presentation
| Parameters | All patients (n=235) | Survivors (n=215) | Non-survivors (n=20) | P |
|---|---|---|---|---|
| Age (yr) | 50 (40-60) | 50 (40-60) | 51 (40.5-60) | 0.92 |
| Sex (M/F) | 160/85 | 146/79 | 14/6 | >0.99 |
| Duration of symptoms (days) | 4 (2-5) | 4 (3-5) | 3 (2-5) | 0.18 |
| Comorbid illness | ||||
| Hypertension (yes/no) | 65/170 | 62/153 | 3/17 | 0.30 |
| Diabetes mellitus (yes/no) | 54/181 | 51/164 | 3/17 | 0.57 |
| CAD (yes/no) | 13/222 | 13/202 | 0/20 | 0.61 |
| CKD (yes/no) | 22/213 | 19/196 | 3/17 | 0.41 |
| CLD (yes/no) | 10/225 | 8/207 | 2/18 | 0.21 |
| COPD (yes/no) | 5/230 | 5/210 | 0/20 | >0.99 |
| Malignancy (yes/no) | 26/209 | 24/191 | 2/18 | >0.99 |
| Laboratory investigations | ||||
| Haemoglobin (g/dl) (n=184) | 11.5 (9.8-13.3) | 11.5 (9.8-13.2) | 12 (8.3-13.4) | 0.87 |
| Total leucocyte count unit (cells/µl) (n=186) | 9000 (6,200-12,400) | 8600 (5,890-12,000) | 13,500 (10,500-15,800) | <0.001 |
| Absolute neutrophil count (cells/µl) (n=132) | 7042 (4,020-10,400) | 6300 (3,745-9,856) | 11,334 (8,837-13,462) | <0.001 |
| Absolute lymphocyte count (cells/µl) (n=134) | 1388 (1,020-1,866) | 1380 (951-1,833) | 1760 (1,326-2,043) | 0.17 |
| Platelet count (103/µl) (n=181) | 169 (112-242) | 166 (111-241) | 184 (150-320) | 0.16 |
| Prothrombin time (sec) (n=54) | 13.8 (12.7-15.6) | 13.5 (12.7-15.3) | 15.6 (14.8-19.7) | <0.05 |
| INR (n=54) | 1.17 (1.09-1.32) | 1.13 (1.07-1.3) | 1.3 (1.3-1.73) | <0.05 |
| Serum creatinine (mg/dl) (n=189) | 1 (0.8-1.5) | 1 (0.8-1.5) | 1.2 (0.9-1.5) | 0.28 |
| Serum bilirubin (mg/dl) (n=123) | 0.8 (0.5-1.35) | 0.85 (0.5-1.35) | 0.6 (0.5-0.9) | 0.32 |
| Arterial lactate (mmol/l) (n=122) | 1.9 (1.3-3.2) | 1.8 (1.25-2.75) | 4.1 (2.4-6.4) | 0.002 |
Data expressed as proportion or median (IQR); Mann-Whitney U-test or Fisher's exact test applied as applicable. IQR, interquartile range; CAD, coronary artery disease; CKD, chronic kidney disease; CLD, chronic liver disease; COPD, chronic obstructive pulmonary disease; INR, international normalized ratio