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. 2021 Jan 29;14:229–248. doi: 10.2147/JPR.S269530

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© 2021 Eissa et al.

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Dose finding process for tapentadol oral solution and intravenous infusion for the age range preterm neonates to children <18 years of age.

Notes:^aNCT01134536, ^bNCT01729728, ^cNCT02221674, ^dEudraCT2014-002259-24, ^eEudraCT2012-004359-35, NCT02081391

Abbreviations: DR, dose recommendation; N, number; PB, physiologically based; PK, pharmacokinetic; Pop, population.