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. 2021 Feb 2;16(2):e0243894. doi: 10.1371/journal.pone.0243894

Table 5. Other psychological outcomes at baseline, 12, 24 and 36 months.

Baseline 12 months 24 months 36 months
n mean (95% CI) n mean (95% CI) n mean (95% CI) n mean (95% CI)
Kidscreen-52 HRQOL
Parent report CBCL t-scores Physical wellbeing 42 44.9(41.4, 48.5) 36 40.4(37.5, 43.3) 14 40.5(36.8, 44.2)
Psychological Wellbeing 41 39.8(36.7, 42.8) 36 39.0(35.4, 42.6) 14 42.4(36.9, 48)
Moods and Emotions 41 40.6(37.6, 43.6) 36 41.2(37.3, 45.1) 14 42.5(36.3, 48.7)
Self-perception 42 34.6(32.6, 36.5) 36 34.8(32.0, 37.5) 14 34.8(31.3, 38.2)
Autonomy 42 46.2(43.2, 49.2) 36 48.2(45.0, 51.4) 14 46.7(41, 52.4)
Parent relations and home life 42 48.1(44.5, 51.6) 35 46.7(42.9, 50.5) 14 49.5(44.1, 54.9)
Social support and peers 39 48.0(44.7, 51.4) 36 51.9(48.4, 55.3) 13 51.4(45.6, 57.2)
School environment 42 38.2(35.0, 41.4) 35 39.4(35.3, 43.4) 13 43.7(36, 51.3)
Social acceptance 39 44.7(40.7, 48.7) 32 42.3(38.1, 46.4) 13 43.5(35.9, 51.2)
Financial resources 42 37.9(33.9, 41.9) 36 35.8(31.5, 40.2) 14 36.3(26.4, 46.3)
Self-report t-scores Physical wellbeing 42 45.1(41.8, 48.5) 36 41.5(38.0, 45.0) 13 43.9(38.9, 48.9)
Psychological Wellbeing 42 43.0(39.6, 46.4) 36 41.1(37.0, 45.2) 14 51(45.8, 56.2)
Moods and Emotions 42 46.3(42.7, 49.9) 36 43.9(40.4, 47.3) 14 50.1(45.5, 54.7)
Self-perception 42 38.8(36.7, 40.9) 36 37.9(35.1, 40.6) 14 43.1(39.9, 46.2)
Autonomy 42 46.6(43.6, 49.6) 36 46.7(42.9, 50.5) 13 51.9(47.4, 56.4)
Parent relations and home life 42 49.7(46.2, 53.2) 36 48.7(45.2, 52.3) 14 58.4(53.3, 63.5)
Social support and peers 37 45.6(42.5, 48.7) 35 48.1(44.6, 51.6) 14 49.7(44.3,55.1)
School environment 41 45.9(42.3, 49.4) 36 44.7(39.7, 49.7) 14 49(43.6, 54.3)
Social acceptance 41 47.4(43.5, 51.3) 33 45.5(40.9, 50.1) 13 53.6(46.3, 60.8)
Financial resources 42 42.2(38.1, 46.3) 34 43.2(38.2, 48.1) 14 46.3(39.1, 53.5)
Body image scale Overall score 42 3.1(2.8, 3.3) 40 3.2(3.0, 3.4) 16 3(2.7, 3.2) 8 3.1(2.4, 3.7)
Primary characteristics score 42 4.5(4.2, 4.7) 39 4.3(4.2, 4.5) 16 4.5(4.3, 4.7) 8 4.2(3.9, 4.5)
Secondary characteristics score 41 2.9(2.6, 3.1) 40 3(2.8, 3.3) 16 2.9(2.5, 3.2) 8 2.9(2, 3.8)
Neutral characteristics score 42 2.5(2.203, 2.707) 40 2.7(2.5, 3.0) - -
Utrecht Gender dysphoria score Median (IQR) 41 4.8(4.6, 5.0) 40 4.7(4.6, 5.0) 18 4.7(4.3, 5.0)
Clinical outcome
CGAS global score Mean (95% CI) 42 62.9(59.6, 66.2) 35 64.1(59.9, 68.3) 18 65.7(59.6, 71.8) 12 66.0(58.1, 73.9)

Note: Change in outcomes in this Table were not formally tested.