Table 4. Energy and dissociation constants of interaction of Spike protein with host ACE2.
Docked structure with ACE2 | Binding Affinity (Kcal/mol) | Dissociation constant (M) | ACE2 Expression (FPKM) in Sample |
---|---|---|---|
RK100 | -50.6 | 7.8E-38 | 0.5576 |
KN318 | -49.9 | 2.6E-37 | 4.1271 |
TC469 | -49.9 | 2.6E-37 | 0.1397 |
KP1125 | -49.9 | 2.6E-37 | 1.5134 |
KN443 | -55.8 | 1.3E-41 | 0.3940 |
RK1090 | -55.8 | 1.3E-41 | 0.4303 |
RR1191 | -55.8 | 1.3E-41 | 0.4722 |