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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Pharmacol Biochem Behav. 2020 Dec 29;201:173093. doi: 10.1016/j.pbb.2020.173093

Figure 7. Examples of sensors compatible with fiber photometry calcium imaging.

Figure 7

The mosaic figure above shows example peri-event traces from sensors used to detect cellular activity (GCaMP6, GCaMP7, or RCaMP) or to detect neurotransmitter binding for dopamine (dLight, GRABDA), GABA (iGABASnFr), glutamate (iGluSnFr), acetylcholine (iAchSnFr), or serotonin (iSEroSnFr). The traces were collected under different experimental conditions (e.g., reward delivery or footshock), but for each trace the fiber photometry data has been aligned to a relevant behavioral event (dotted line). As seen by the variability of responses, each of the currently available sensors is not only compatible with fiber photometry calcium imaging, but can also demonstrate behaviorally relevant increases, decreases, or even biphasic responses.