Table 4.
Comparison of recovered thyroid function versus persistent low T3 syndrome
| Recovery of T3 plasma level n = 11 |
Persistent low T3 syndrome n = 15 |
p value | |
|---|---|---|---|
| Age (years) | 56.8 ± 20.6 | 55.4 ± 16 | 0.84 |
| Sex, female | 50.0 | 53.3 | 0.87 |
| APACHE II | 13.6 ± 5.22 | 18.3 ± 7 | 0.07 |
| SOFA | 8.8 ± 3 | 10.5 ± 3.9 | 0.23 |
| Focus | |||
| Abdominal | 75 | 40 | 0.07 |
| Respiratory | 8.3 | 26.7 | 0.23 |
| Urinary | 8.3 | 20 | 0.41 |
| Endovascular | 6.7 | NC | |
| Other | 8.3 | 6.7 | 0.87 |
| Charlson index | 2.8 ± 2.6 | 4.2 ± 2.7 | 0.19 |
| Days of hospitalization | 15.6 ± 5.7 | 13.8 ± 13.5 | 0.68 |
| Mortality 28 days | 0 | 66.7% | 0.013 |
| T3 at the diagnosis of shock (ng/dL) | 53.15 ± 13.7 | 48.9 ± 20 | 0.54 |
| T3 day 7 | 73.9 ± 20 | 54.4 ± 17.9 | 0.015 |
| T3 day 14 | 99.8 ± 28 | 44.6 ± 11.7 | 0.0001 |
| T3 day 21 | 73.2 ± 20 | 62.5 ± 9.9 | 0.084 |
| Lactate 0 hour (mmol/L) | 5.4 ± 4.1 | 3.04 ± 3.4 | 0.12 |
| Lactate 24 hours (mmol/L) | 3.1 ± 2.7 | 3.5 ± 4.4 | 0.79 |
| Clearance lactate 24 hours | 42 | -15 | 0.0046 |
| Lactate 48 hours (mmol/L) | 2.4 ± 1.6 | 2.3 ± 1.1 | 0.85 |
| Lactate 72 hours (µ/kg/min) | 1.7 ± 0.9 | 2.22 ± 1.58 | 0.33 |
| Clearance lactate 72 hours | 68.7% | 36.5% | 0.11 |
| NDL day 1 (µ/kg/min) | 0.31 ± 0.26 | 0.79 ± 0.58 | 0.017 |
| NDL day 2 (µ/kg/min) | 0.46 ± 0.38 | 0.63 ± 0.6 | 0.41 |
| NDL day 3 (µ/kg/min) | 0.14 ± 0.05 | 0.55 ± 0.68 | 0.058 |
| NDL day 4 (µ/kg/min) | 0.05 ± 0.05 | 0.68 ± 0.7 | 0.0068 |
T3 - triiodothyronine; APACHE II - Acute Physiology and Chronic Health Evaluation II; SOFA - Sequential Organ Failure Assessment; NA - not applicable; OR - odds ratio; 95%CI - 95% confidence interval NDL - noradrenaline. Results expressed as mean ± standard deviation or %.