Figure 1. Fiber Optic implantation in Mouse.

A. Ceramic ferrule orientation for optic fiber and example final optic fiber implant. B. Optimal laser beam shape after polishing is a clean circle with high light output, and if polished and cleaved well, contains concentric circles. In comparison, poor laser beam shapes are fuzzy or misshaped circles with lower light output. C. Mouse skull exposed with diagram indicating bregma and lambda for stereotaxic injection. D. Mouse with bilateral fiber optic implants, pink skull cap (acrylic), and metal holding bar (18G needle).