Figure 6.
Antitumor Effects of T-01 In Vivo in Immunodeficient Mice
(A) Treatment schema. GRANTA-519 or ED-40515(+) cells were subcutaneously implanted into the left flank of SCID Beige mice. Mock or T-01 (0.2 × 106 or 1.0 × 106 PFUs) was injected into the established tumor on days 0 and 3. The tumor size was measured every 2 or 3 days. (B) Tumor growth curves (n = 7 and 8 for GRANTA-519 and ED-40515(+), respectively). Arrows indicate injection of mock or T-01. The data are shown as the mean ± SE. Statistical analysis was conducted using non-repeated-measures ANOVA followed by Dunnett’s test. ∗∗p < 0.01.