Table 1.
Patient Characteristics
| Patient ID | Age | Sex | ECOG | Tumor Sizea (cm) | Tumor Location | Pre-treatment TNM | Pre-treatment Stage | Histology | Delivery Method | Final TNM | Surgical Staging |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dose Level 1: 2.5 × 1011vp | |||||||||||
| 1LU02 | 74 | M | 0 | 9.4 | RLL | T4N0 | IIIA | SCC | VATS | T4N2 | IIIB |
| 1LU04 | 55 | M | 1 | 4.0 | RLL | T2aN0 | IB | SCC | EBUS | T2bN0 | IIA |
| 1LU05 | 57 | M | 1 | 5.4 | LUL | T3N0 | IIB | SCC | EBUS | T3N1 | IIIA |
| Dose Level 2: 5 × 1011vp | |||||||||||
| 2LU01 | 65 | M | 1 | 9.8 | RUL | T4N0 | IIIA | SCC | EBUS | T4N0 | IIIA |
| 2LU02 | 72 | M | 1 | 3.2 | RUL | T2aN0 | IB | adeno | EBUS | T2aN0 | IB |
| 2LU04 | 77 | M | 1 | 2.6 | LLL | T1cN0 | IA | SCC | EBUS | T2aN0 | IB |
| Dose Level 3: 1 × 1012vp | |||||||||||
| 3LU01 | 65 | M | 0 | 4.3 | RLL | T2bN0 | IIA | SCC | EBUS | T3N2 | IIIB |
| 3LU02 | 70 | M | 1 | 14.8 | LLL | T4N0 | IIIA | sarco | EBUS | T4N0 | IIIA |
| 3LU06 | 80 | F | 0 | 1.8/4 | RUL/RLL | T2aN0 | IB | adeno | EBUS | T3N2 | IIIB |
| 3LU08 | 63 | F | 0 | 6.5 | RLL | T3N0 | IIB | SCC | EBUS | T3N0 | IIB |
| 3LU12 | 64 | M | 0 | 3.3 | RUL | T2aN0 | IB | adeno | EBUS | T1cN0 | IA |
| 3LU13 | 62 | F | 0 | 3.6 | RUL | T2aN0 | IB | adeno | EBUS | T3N0 | IIB |
SCC, squamous cell carcinoma; VATS, video-assisted thoracoscopic surgery; EBUS, endobronchial ultrasound; adeno, adenocarcinoma; sarco, sarcomatoid carcinoma.
a
Largest diameter from baseline imaging.