Figure 3.

Retinal Thickness Topography as a Guide for Retinal Gene Therapy

Montage built from overlapping 30o X 20o “raster” (or volume) scans vertically separated by 0.1 mm from a young patient with RPE65-IRD. Retinal thickness is mapped to a pseudocolor scale shown to the right. Overlaid are 9-mm-long SD-OCT cross-sections sampling regions with a high likelihood of demonstrating detectable photoreceptors. In young subjects the decline in thickness of a visible ONL with increasing distance from the fovea generally corresponds to the decline in overall retinal thickness.