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. 2020 Oct 27;38(1):24–51. doi: 10.1007/s12325-020-01525-5

Table 1.

Features of an ideal first-line drug in glaucoma

Feature Fixed combination dorzolamide/timolol
Efficacy Yes
Safety Yes
Once daily dosing No
Minimal peak/trough IOP control Yes
Flexibility of dosing time of day No
Preservative-free available Yes
Cost-effective Yes
Brand versus generic Yes
Long-term published evidence Yes
Can be used in patients with allergy to sulfonamides Yes