Table 3.

Total amount of N-acetylcysteine excreted in urine after single- (Days 1–2) and multiple-dose (6–7) administration, and fraction of N-acetylcysteine excreted in urine and renal clearance after single- (Days 1–2) and multiple-dose (6–7) administration

	Days 1–2			Days 6–7
	Asian (n = 15)	Caucasian (n = 15)		Asian (n = 15)	Caucasians (n = 15)
Ae0–t, µg	21,963.2 ± 7331.4	22,775.4 ± 6191.0	Ae0–t,ss, µg	21,599.4 ± 7846.0	20,523.8 ± 5592.7
Fe0–t, %	3.7 ± 1.2	3.8 ± 1.0	NA	–	–
CLr, L/h	2.0 ± 0.4	2.0 ± 0.6a	NA	–	–

All data are presented as mean ± SD

CL clearance, NA not applicable, SD standard deviation

^an = 13