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. 2020 Jun 30;23(2):325–334. doi: 10.1007/s12094-020-02422-7

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© The Author(s) 2020

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Fig. 2 — ADMA regulated GC cell migration and invasion but had no treatment on growth in vitro. a, b CCK8 assay demonstrating the influence of different concentrations of ADMA on the proliferation rate of AGS and MGC803 cells. Data were expressed as mean ± SD of three independent experiments (NS indicates no statistical significance). c, d Relative migration of the AGS and MGC803 through an uncoated filter toward serum-containing medium in a Boyden chamber assay. Data were expressed as mean ± SD of three independent experiments (*P < 0.05). e, f Relative motility as determined by the ability of AGS and MGC803 to close a wound made by creating a scratch through a lawn of confluent cells. Data were expressed as mean ± SD of three independent experiments (*P < 0.05). G and H, Relative invasion of the GC cells (AGS and MGC803) through a layer of Matrigel coated on the filter of a Boyden chamber. Data were expressed as mean ± SD of three independent experiments (*P < 0.05)