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. Author manuscript; available in PMC: 2022 Feb 15.
Published in final edited form as: J Immunol. 2021 Jan 8;206(4):751–765. doi: 10.4049/jimmunol.2001042

Fig. 6. scRNA-seq reveals predominant granulocyte infiltrates in the galea and bone flap following S. aureus craniotomy infection.

Fig. 6.

Viable CD45+ cells were isolated from the galea (n= 11,771 cells) and bone flap (n= 6,672 cells) of mice (n=10) at day 7 following S. aureus craniotomy infection by FACS and processed for scRNA-seq. Transcriptional clusters in the (A) galea and (D) bone flap were identified by SingleR and are presented as UMAP plots. Heatmaps and trajectory analysis of granulocyte clusters in the (B and C) galea and (E and F) bone flap.