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. 2021 Jan 20;11:625630. doi: 10.3389/fimmu.2020.625630

Figure 2.

Figure 2

Elevated BAFF expression associates with decreased apoptosis of B cells in NPs with eLTs. (A) Immunofluorescence staining of NP tissues shows BAFF-positive cells in NPs with and without eLTs. Original magnification × 400. (B) The numbers of BAFF+ cells per high power filed in NPs with or without eLTs. (C) Double immunofluorescence staining of consecutive NP tissue sections of those shown in Figure 2A demonstrates active caspase-3+CD20+ B cells in NPs with and without eLTs. Original magnification × 400. (D) The percentages of active caspase-3+CD20+ B cells in total CD20+ B cells in NPs with or without eLTs. (E–G) The correlation between the percentages of active caspase-3+CD20+ B cells in total B cells and the numbers of BAFF+ cells in total NPs (E), NPs without eLTs (F), and NPs with eLTs (G). BAFF, B cell-activating factor; NPs, nasal polyps; eLTs+, with ectopic lymphoid tissues; eLTs-, without ectopic lymphoid tissues. ***P < 0.001.