Table 4.
. Relationship of serum estrogen level and response (a) and change in FFNP uptake after estradiol challenge (b).
| (a) Relationship between serum estrogen level and clinical response (n = 37) | ||||
|---|---|---|---|---|
| Clinical effect of endocrine therapy | ||||
| Response (n = 24) Median (Q1–Q3)a |
No response (n = 13) Median (Q1–Q3) |
pb | ||
| Prior to estradiol challenge | ||||
| Baseline estradiol level | 15.1 (13.4–19.1) | 13.3 (8.6–19.3) | 0.37 | |
| After estradiol challenge | ||||
| Change of estradiol against baselinec | 9.9 (5.8–15.5) | 13.2 (10.2–21.8) | 0.25 | |
| (b) Relationship between serum estradiol level and FFNP uptake change (n = 37) | ||||
|---|---|---|---|---|
| FFNP uptake change | ||||
| Spearman correlation coefficients | pd | |||
| Prior to estradiol-challenge test | ||||
| Baseline estradiol level | 0.25 | 0.14 | ||
| After estradiol-challenge test | ||||
| Change rate of estradiol levelc | −0.23 | 0.17 | ||
aQ1 = 25th percentile, Q3 = 75th percentile.
bKruskal-Wallis test.
cCalculated as (estradiol level after estradiol challenge − baseline estradiol level)/baseline estradiol level.
dSpearman-Brown test.