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. 2021 Feb 2;11:2799. doi: 10.1038/s41598-020-80687-2

Table 5.

Connectivity in motor network before (scan 1) and after (scan 2) cross-sex hormone treatment in TR persons, (controls were not treated).

Between-group comparisons, scan 1
Motor network Con > TrM R sensory motor cortex, (leg area)a 5.7 1.0 6 − 6 40
Con > TrW L sensory motor cortex, (body area) 13.4 1.0 − 36 − 26 38
Between-group comparisons, scan 1, and scan 2
Con > TrM L sensory motor cortex (leg area)a 7.9 1.0 12 − 18 38
Con > TrW L sensory motor cortex, (body area) 7.8 1.0 − 32 − 26 42
Within-group comparison, scan 1 > scan 2 or the reverse
Controls (scan 1 > scan 2) No significant clusters
TrM (scan2 > scan 1) No significant clusters
TrW (scan2 > scan 1) No significant clusters
Between-group comparisons, scan 2 > scan 1
TrM > controls No significant clusters
TrW > controls No significant clusters

mPFC, mesial prefrontal cortex; lPFC, lateral prefrontal cortex; ACC, anterior cingulate cortex.

Calculations at 1 − p > 0.98, cluster size > 1.0 cc.

aCovers both right and left side.