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. 2021 Feb 2;11:2813. doi: 10.1038/s41598-021-82288-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Blood concentrations of irisin, myostatin, sclerostin, OPG, 25(OH)D and PTH in male amateur runners before and after the Visegrad Marathon. (a) irisin, (b) myostatin, (c) sclerostin, (d) OPG, (e) 25(OH)D, (f) PTH. 1: before marathon; 2: 24 h after the marathon; 3: 72 h after the marathon. ** p < 0.01 significant differences between measurements before and 24 h after the marathon. * p < 0.01 significant differences between measurements before and 24 h after the marathon. † p < 0.05 significant differences between measurements 24 h and 72 h after the marathon. ^§§ p < 0.01 significant differences between measurements before and 72 h after the marathon. ^§ p < 0.05 significant differences between measurements before and 72 h after the marathon.